Finding innovative ways to treat pain

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“This bench to bedside research is very exciting and will have a major impact on the management of neurological diseases, particularly neuropathic pain. This research will help us understand the response of cells to different drugs and different stimulation responses, and allow us to provide individualized or personalized medical therapy for patients suffering with neuropathic pain.”

Akbar Panju , Medical Director of the Michael G. DeGroote Institute for Pain Research and Care

Finding innovative ways to treat pain

There are a lot of unanswered questions when it comes to understanding pain and the best ways to treat it. The nervous system is complex and scientists can’t simply take cell samples from patients for study – the procedure would itself cause discomfort, and isn’t feasible as patients can’t donate their own neural cells for testing. McMaster University’s Mick Bhatia and Karun Singh have come up with the next best thing: a way to convert adult human blood cells to both central nervous system neurons as well as to neurons in the peripheral nervous system. Using this method, obtaining blood samples and converting these into neurons for testing in the lab becomes an easy and painless procedure.

This opens new doors for pain research and ways to treat it with more effective medication.